Increased Brain Tumor Risk from Wireless Phone Use:
2017 Supplement to the BioInitiative Report
In May, 2011, radio frequency radiations (RFR) was classified every bit a ”possible” human carcinogen (Group 2B) yesteryear the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO) based upon an increased run a jeopardy for glioma too acoustic neuroma observed inwards human epidemiological studies.
Since then, RFR exposure has increased inwards nearly countries every bit few countries took whatsoever precautionary actions due to confusion sowed yesteryear the wireless industry. The emerging 5th generation of wireless technology, known every bit 5G, volition farther increment RFR exposure.
The RFR exposure limits adopted yesteryear nearly countries were established inwards 1998 yesteryear the International Commission on Non-Ionizing Radiation Protection (ICNIRP). The limits were based on short-term thermal (heating) effects from RFR too ignored non-thermal biological effects.
Although the ICNIRP guidelines were updated inwards 2009, they withal produce non comprehend long-term wellness risks from non-thermal exposures. ICNIRP’s electrical flow RFR exposure limits are two to 10 W/m2 depending on frequency. ICNIRP has xiv members; many convey ties to industries that desire to keep these permissive guidelines.
In contrast to ICNIRP, inwards 2007 27 RFR scientists reviewed the literature on non-thermal wellness effects too released the BioInitiative Report. In 2012 when the study was updated, the authors concluded that wellness risks tin laissez passer on the axe endure observed alongside an RFR exposure of xxx to threescore μW/m2. Applying a security component of 10, they proposed a precautionary target degree of 3–6 μW/m2 which corresponds to 3 hundred K to 3 1000000 times less exposure than the ICNIRP limits allow.
This supplement to the BioInitiative Report written yesteryear Lennart Hardell too Michael Carlberg examines the case-control enquiry on encephalon tumor run a jeopardy published since 2011 when IARC classified RFR every bit “possibly carcinogenic.”
The study finds consistent bear witness of increased run a jeopardy for glioma too acoustic neuroma associated alongside mobile telephone too cordless telephone use. These results are supported yesteryear results from animate existence studies showing genotoxic, co-carcinogenic, too tumor-promoting effects from RFR. Animal enquiry finds bear witness for an indirect machinery for RFR-induced cancer, namely, oxidative stress on the cells leading to costless radical production too deoxyribonucleic acid damage.
The supplement concludes that RFR should at i time endure classified every bit “carcinogenic to humans” (Group 1) based on the IARC Definition for this category:
“an agent may endure placed inwards this category when bear witness of carcinogenicity inwards humans is less than sufficient merely in that location is sufficient bear witness of carcinogenicity inwards experimental animals too potent bear witness inwards exposed humans that the agent acts through a relevant machinery of carcinogenicity."
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Lennart Hardell, Michael Carlberg. Use of Wireless Phones too Evidence for Increased Risk of Brain Tumors: 2017 Supplement. BioInitiative Working Group, November, 2017.
The supplement to the BioInitiative Report is available at: http://bit.ly/bioinitbrain2017.
April 13, 2017
Evaluation of Mobile Phone too Cordless Phone Use too Glioma Risk
Using the Bradford Hill Viewpoints from 1965 on Association or Causation
"The nine Bradford Hill viewpoints on association or causation regarding RF radiations too glioma risk seem to endure fulfilled inwards this review. Based on that nosotros conclude that glioma is caused yesteryear RF radiation. Revision of electrical flow guidelines for exposure to RF radiations is needed."
This review newspaper yesteryear Michael Carlberg too Lennart Hardell evaluates the describe of the scientific bear witness to create upwards one's hear whether in that location is a causal human relationship betwixt a run a jeopardy component too an associated illness -- namely, wireless (cellphone too cordless) telephone utilisation too glioma, the nearly mutual encephalon cancer. The newspaper applies the nine perspectives developed yesteryear Sir Austin Bradford Hill to the peer-reviewed information pertaining to this wellness risk.
The authors allege that official bodies that convey reviewed the bear witness on mobile telephone utilisation too wellness risks convey been dominated yesteryear individuals alongside conflicts of interest. Moreover, these reviewers convey relied upon information from methodologically unsound studies, including the Danish Cohort Study too a UK of Britain too Northern Republic of Ireland cohort study, to dismiss the bear witness from case-control studies.
The authors allege that official bodies that convey reviewed the bear witness on mobile telephone utilisation too wellness risks convey been dominated yesteryear individuals alongside conflicts of interest. Moreover, these reviewers convey relied upon information from methodologically unsound studies, including the Danish Cohort Study too a UK of Britain too Northern Republic of Ireland cohort study, to dismiss the bear witness from case-control studies.
Drawing upon several lines of research, the authors introduce a compelling declaration for their decision that glioma is caused yesteryear radio frequency (RF) radiation. The newspaper recommends that the electrical flow guidelines for RF exposure must endure revised to protect the population from exposure to low-intensity, non-thermal levels of radio frequency radiation.
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Carlberg M, Hardell L. Evaluation of Mobile Phone too Cordless Phone Use too Glioma Risk Using the Bradford Hill Viewpoints from 1965 on Association or Causation. Biomed Research International. 2017;2017:9218486. doi: 10.1155/2017/9218486. Epub 2017 Mar 16.
Objective. Bradford Hill's viewpoints from 1965 on association or causation were used on glioma run a jeopardy too utilisation of mobile or cordless phones.
Methods. All nine viewpoints were evaluated based on epidemiology too laboratory studies.
Results. Strength: meta-analysis of case-control studies gave odds ratio (OR) = 1.90, 95% confidence interval (CI) = 1.31-2.76 alongside highest cumulative exposure.
Consistency: the run a jeopardy increased alongside latency, meta-analysis gave inwards the 10+ years' latency grouping OR = 1.62, 95% CI = 1.20-2.19.
Specificity: increased run a jeopardy for glioma was inwards the temporal lobe. Using meningioma cases every bit comparing grouping withal increased the risk.
Temporality: highest run a jeopardy was inwards the 20+ years' latency group, OR = 2.01, 95% CI =1.41-2.88, for wireless phones.
Biological gradient: cumulative utilisation of wireless phones increased the risk.
Plausibility: animate existence studies showed an increased incidence of glioma too malignant schwannoma inwards rats exposed to radiofrequency (RF) radiation. There is increased production of reactive oxygen species (ROS) from RF radiation.
Coherence: in that location is a alter inwards the natural history of glioma too increasing incidence.
Experiment: antioxidants reduced ROS production from RF radiation.
Analogy: in that location is an increased run a jeopardy inwards subjects exposed to extremely low-frequency electromagnetic fields.
Conclusion. RF radiations should endure regarded every bit a human carcinogen causing glioma.
Abstract for opened upwards access paper: http://bit.ly/2p1ovBU
Also see:
Key Cell Phone Radiation Research Studies
Cell Telephone As Well As Cordless Telephone Role Causes Encephalon Cancer: Novel Review
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